Leaves

Akkapana (Kalanchoe pinnata): The Life Plant and Its Cardiac Glycosides

(Kalanchoe pinnata) Last updated Jul 17, 2026
Akkapana (Kalanchoe pinnata): The Life Plant and Its Cardiac Glycosides
Image Credit: Ruhan, CC BY-SA 4.0 <https://creativecommons.org/licenses/by-sa/4.0>, via Wikimedia Commons

Quick Facts

Sinhala Name අක්කපාන
English Name Life Plant (Air Plant)
Scientific Name Kalanchoe pinnata
Plant Family Crassulaceae
Parts Used Leaves
Common Uses Kidney stones, wounds, urinary health

Akkapana (Kalanchoe pinnata) earns its English names — Life Plant, Miracle Leaf — honestly enough: drop a detached leaf on soil and plantlets sprout from every notch along its edge. In Sri Lanka it is the plant people chew for kidney stones. It also contains compounds that act on the heart, which is a fact worth carrying alongside the enthusiasm.

Botanical and Cultural Background

Akkapana is a succulent of the Crassulaceae family, native to Madagascar and thoroughly naturalised here, with thick fleshy scalloped leaves and pendulous bell-shaped flowers. Its vegetative reproduction from leaf margins is what made it an ornamental curiosity and gave it its names.

Traditional Uses in Sri Lankan Medicine

Kidney and bladder stones

Its most famous local use — fresh leaves chewed on an empty stomach, or the juice taken daily.

Wounds and boils

A leaf warmed over a flame, crushed and bound over a cut, burn or boil. This external use is the plant's most defensible one.

Insect bites

Crushed leaf applied to stings and bites.

Gastritis

Leaf juice taken traditionally for acidity.

What the Research Shows

Research on Kalanchoe pinnata reports anti-inflammatory, antimicrobial, wound-healing and hepatoprotective activity in laboratory and animal models, and has identified flavonoids, phenols and — importantly — bufadienolides.

Those bufadienolides are cardiac glycosides. They act on the heart in the same manner as digoxin, and they are the reason Kalanchoe species cause fatal poisoning in grazing livestock in southern Africa, where the syndrome is well documented. In humans the risk from a few leaves is low — Sri Lankans have chewed akkapana for generations — but "low from a few leaves" is not "harmless in any quantity", and this plant does not deserve to be treated as a salad.

On stones specifically, human clinical evidence is absent. Laboratory work on antiurolithiatic activity exists; the confident claim that akkapana dissolves calcium oxalate stones so they "pass painlessly" is not supported.

How Akkapana Is Prepared

For stones (traditional): Two or three washed fresh leaves chewed in the morning.

Wound poultice: A leaf softened over a flame, crushed and bound over the wound.

Safety and Precautions

Never put akkapana juice — or any plant juice — into an ear or an eye. This is the clearest correction on this page, because tradition recommends both. The eye is delicate and unforgiving: non-sterile plant material can cause corneal injury and introduce infection, and conjunctivitis and styes have safe, effective treatments. If the eardrum is perforated, and you cannot know whether it is, liquid in the middle ear can cause lasting damage and hearing loss. Eye and ear symptoms need a doctor.

Do not consume akkapana in large amounts or for long periods. It contains cardiac glycosides. Traditional use — a few leaves — has a long record, but prolonged or heavy consumption is genuinely unwise, and anyone with a heart condition or taking digoxin, beta-blockers or other cardiac medication should not take it internally at all without medical advice. Do not take it in pregnancy or while breastfeeding, and do not give it to children.

Kidney stones need imaging. A stone large enough to matter will not be chewed away, and it can obstruct the kidney. Severe pain, fever with urinary symptoms, or blood in the urine means go to hospital. Because akkapana acts as a diuretic, do not combine it with prescription diuretics without supervision.

Scientific References

  • Kamboj, A. & Saluja, A.K. (2009). Bryophyllum pinnatum (Lam.) Kurz.: Phytochemical and pharmacological profile: A review. Pharmacognosy Reviews, 3(6), 364–374.
  • Yadav, N.P. & Dixit, V.K. (2003). Hepatoprotective activity of leaves of Kalanchoe pinnata Pers. Journal of Ethnopharmacology, 86(2–3), 197–202.
  • McKenzie, R.A. & Dunster, P.J. (1986). Hearts and flowers: Bryophyllum poisoning of cattle. Australian Veterinary Journal, 63(69), 222–227.
  • Supratman, U., Fujita, T., Akiyama, K., et al. (2001). Anti-tumor promoting activity of bufadienolides from Kalanchoe pinnata. Bioscience, Biotechnology, and Biochemistry, 65(4), 947–949.
  • Jayaweera, D.M.A. (1982). Medicinal Plants (Indigenous and Exotic) Used in Ceylon. National Science Council of Sri Lanka, Colombo.

Frequently Asked Questions

Can akkapana juice be used for earache or eye infections?

No — never put plant juice into an ear or an eye, even though tradition recommends both. The eye is delicate: non-sterile plant material can cause corneal injury and introduce infection, and styes and conjunctivitis have safe effective treatments. If the eardrum is perforated — and you cannot know — liquid in the middle ear can cause lasting hearing damage.

Is it true akkapana affects the heart?

Yes. It contains bufadienolides, which are cardiac glycosides acting on the heart much as digoxin does — they cause fatal poisoning in grazing livestock in southern Africa. The risk from a few chewed leaves is low, and Sri Lankans have done it for generations, but that is not the same as harmless in any quantity. Don't take it long-term, and not at all if you take cardiac medication.

Does akkapana dissolve kidney stones?

Human evidence is absent. Laboratory work on anti-stone activity exists, but the claim that it dissolves calcium oxalate stones so they pass painlessly isn't supported. A stone large enough to matter won't be chewed away and can obstruct the kidney — stones need imaging and medical assessment.

Why is it called the Life Plant?

Drop a detached leaf on soil and tiny plantlets sprout from every notch along its edge — it reproduces vegetatively from the leaf margins. That's also why it's called the Miracle Leaf and the Goethe Plant.

Medical Disclaimer The information on this page is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified physician or Ayurvedic practitioner before using any herbal remedy, especially if you are pregnant, nursing, taking medication, or have a medical condition. Read our full disclaimer
Nishnath Thaweesha

Edited by Nishnath Thaweesha

I am deeply connected to nature, animals, and wildlife. Exploring the healing power of the natural world and traditional herbal wisdom is my lifelong passion. As a Human-in-the-Loop (HITL) Editor, I rigorously fact-check, curate, and verify all botanical content against scientific journals to ensure the highest standards of accuracy and trust.


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